Re-engineered T-cells to fight Cancer

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An Immune System Trained to Kill Cancer

CLOSE-UP Dr. Carl June examined re-engineered T-cells last week in his Philadelphia lab.

PHILADELPHIA — A year ago, when chemotherapy stopped working against his leukemia, William Ludwig signed up to be the first patient treated in a bold experiment at the University of Pennsylvania. Mr. Ludwig, then 65, a retired corrections officer from Bridgeton, N.J., felt his life draining away and thought he had nothing to lose.